The “fat cells are multiplying” is normal when having surplus calories in the body. The “empty fat cells scream hunger” is something that was suspected basically for ages, but has finally be proven not long ago, the paper is less than half a year old. It had been referred to here on Lemmy, at least to a science or nature article that pointed to the paper.

You’re basically blaming the drug for the person’s inability to psychologically deal with diet.

No, I don’t. I’m just stating facts on how the human body works. With extreme willpower you might be able to counter this for a time, yes. But it will be a serious uphill battle, and the messenger chemicals from the depleted fat cells do not just stop because you will them to. You will just have to live in a state of perpetual raving hunger then. The few who can successfully overcome this for a significant time are rare, indeed.

That’s… Not a side effect.

No, it is just the way this drug works. You take Ozempic, it supresses your hunger feeling, and you automatically change your diet as you are not as hungry anymore.

Problem is that the depleted fat cells still exist, and a depleted fat cell releases signals that scream “I’m hungry! Feed me!”, and the more they are depleted, the louder the call. While you take Ozempic, this is supressed, but as soon as you get off it, your body demands food to re-fill the depleted cells, and will not stopping before it has reached at least the former status quo.

Just like the bounce back effect after a diet, only worse.

If you take ozempic for weight loss but choose to continue eating like shit then it isn’t the drug’s fault.

That’s not how it works. Ozempic simply opresses the hunger feeling, therefor helping you lose weight. Problem is that still existing, but empty/depleted fat cells basically scream “we are hungry”, so as soon as you get off Ozempic, you basically can’t stop eating until you regained at least the former state. That was - for me - the reason not to start on Ozempic, it’s like the “bounce back” effect after a diet, but on steroids. That current research has found other issues (heart problems, ocular nerve damages) just enforced my rejection (I was offered this on a free prescription base).

I think most medications are meant to be accompanied with permanent lifestyle changes where possible. No, you should not take this drug “forever”.

That is a very idealistic view, at least on some medication. With Ozempic, this is basically impossible due to the circumstances written above, with other medications it is simply due to the fact that no “lifestyle changes” can change e.g. genetic defects.

But with Ozempic there is some serious long-term shit going on, which is bad, as you basically have to take this stuff forever or bounce back hard faster than you saying “supersize this burger meal”.

Before going on Ozempic, read up on current medical research (not Facebook or such shit). They discovered some not-so-good long term effects recently.

Alabama is all about family.

This depends on what you are actually looking for, and how you are looking for it.

Do you really need pattern matching, or do you only look for fixed strings? Then other tools may be faster.

If you need case independent search on an upper- and lowercase data set, make a copy that is all upper or all lower, and search there.

If you only search in certain columns, make a copy that only includes these.

Or import the data into a database.

Occasionally, humanity sacrifices a wannabe Christian missionary for them.

I knew it as “New York Second”, and that it is the shortest time interval measurable by science.

Or concrete boots and a coast with nice tides.

The first thing that comes to mind here are prostata problems or kidney stones. While the ring muscles can’t counter the pressure from a full bladder, the other two can seriously obstruct the urinary tract. In case of a kidney stone, it could even be that sharp crystals support or cause a rupture.

Jean-Michel Jarre: Oxygene I-III, Equinoxe, etc.

Kitaro: e.g. Kojiki or Silk Road

Robert Miles: Fable and Children, especially the long versions.

Some of Alan Parsons and Mike Oldfields pieces are good on that behalf, too.

Oh kid, I do this for over forty years now.

But then you’ll need to weigh them down. Pre-corpsed Republicans is cheaper than chains and weights, but I have to admit that the other method may be more satisfying.

What’s those balls on the plate?

Can, yes, but in my experience rarely is.

Soll ich Deine Sätze korrigieren, oder willst Du einfach durch Beispiele Satzbau und Rechtschreibung lernen?

Politik und Nachrichten sind immer interessant. Beim Thema Gaming kann ich nicht mithalten, Zeit für mehr als Solitär habe ich im Allgemeinen nicht.

The killer collective.

We just celebrated 28 years of this development, so 1997. We live here since 2002.