I’m no linux expert, but I think that issues like that are pretty common with a flash boot - based on BIOS boot sequences or similar issues, the drive likely doesn’t have as many permissions or permissions in the right order as a ssd would. As an intermediary step, you could try partitioning your drive first then doing a full install on a small partition.

There’s a recent podcast talking about this if you’re interested - https://omny.fm/shows/better-offline/the-man-that-destroyed-google-search

TLDR; they fired the guy largely responsible for building google search and replaced him with the guy running google ads.